Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

FOXC1 Antikörper (C-Term)

FOXC1 Reaktivität: Human, Maus, Zebrafisch (Danio rerio) WB, IHC (p), ChIP, EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN374336
  • Target Alle FOXC1 Antikörper anzeigen
    FOXC1 (Forkhead Box C1 (FOXC1))
    Bindungsspezifität
    • 11
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 54
    • 33
    • 19
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Zebrafisch (Danio rerio)
    Wirt
    • 55
    • 2
    • 1
    Ziege
    Klonalität
    • 57
    • 1
    Polyklonal
    Konjugat
    • 28
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser FOXC1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 26
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP), Enzyme Immunoassay (EIA)
    Sequenz
    RTSGAFVYDC SKF
    Spezifität
    This antibody detects FOXC1 / FKHL7 / FREAC3 at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse, Zebrafish.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
    Immunogen
    Peptide from C-Terminus of the protein sequence according to NP_001444.2. Genename: FOXC1
    Top Product
    Discover our top product FOXC1 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-1.5 μg/mL. Approx 55 kDa band observed in Human Bone Marrow lysates(calculated MW of 56.5 kDa according to NP_001444.1). Immunohistochemistry: 3 μg/mL. In paraffin embedded Human Kidney shows nuclearstaining of some cells in the glomeruli.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
  • Doucette, Footz, Walter: "FOXC1 Regulates Expression of Prostaglandin Receptors Leading to an Attenuated Response to Latanoprost." in: Investigative ophthalmology & visual science, Vol. 59, Issue 6, pp. 2548-2554, (2019) (PubMed).

    Fatima, Wang, Uchida, Norden, Liu, Culver, Dietz, Culver, Millay, Mukouyama, Kume: "Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation." in: The Journal of clinical investigation, Vol. 126, Issue 7, pp. 2437-51, (2017) (PubMed).

    Ito, Goping, Berry, Walter: "Dysfunction of the stress-responsive FOXC1 transcription factor contributes to the earlier-onset glaucoma observed in Axenfeld-Rieger syndrome patients." in: Cell death & disease, Vol. 5, pp. e1069, (2014) (PubMed).

  • Target
    FOXC1 (Forkhead Box C1 (FOXC1))
    Andere Bezeichnung
    FOXC1 / FKHL7 / FREAC3 (FOXC1 Produkte)
    Synonyme
    ARA antikoerper, FKHL7 antikoerper, FREAC-3 antikoerper, FREAC3 antikoerper, IGDA antikoerper, IHG1 antikoerper, IRID1 antikoerper, RIEG3 antikoerper, FoxC1 antikoerper, fkhl7 antikoerper, freac-3 antikoerper, freac3 antikoerper, igda antikoerper, ihg1 antikoerper, irid1 antikoerper, rieg3 antikoerper, xfd-11 antikoerper, ara antikoerper, FOXC1 antikoerper, foxc1 antikoerper, Fkh1 antikoerper, Mf1 antikoerper, Mf4 antikoerper, ch antikoerper, fkh-1 antikoerper, frkhda antikoerper, CFKH-1 antikoerper, XFD-11 antikoerper, foxc1.2 antikoerper, id:ibd5079 antikoerper, forkhead box C1 antikoerper, forkhead box C1 S homeolog antikoerper, forkhead box C1 L homeolog antikoerper, Forkhead box protein C1 antikoerper, winged helix transcription factor XFD-11 antikoerper, forkhead box C1b antikoerper, FOXC1 antikoerper, Foxc1 antikoerper, foxc1.S antikoerper, foxc1 antikoerper, foxc1.L antikoerper, foxc1-A antikoerper, foxc1b antikoerper
    Hintergrund
    FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.Synonyms: FREAC-3, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3
    Molekulargewicht
    56.8kDa (NP_001444.1).
    Gen-ID
    2296
    NCBI Accession
    NP_001444
    UniProt
    Q12948
    Pathways
    Chromatin Binding, Glycosaminoglycan Metabolic Process
Sie sind hier:
Kundenservice