TRPM7 Antikörper (C-Term)

Produktnummer ABIN374098

Produktdetails anti-TRPM7 Antikörper

Target: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Schwein, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TRPM7 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-TKESESTNSV RLML

Spezifität: This antibody detects TRPM7 at C-term.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Canine (Dog) and Pig.
Species reactivity (tested):Mouse, Rat, Crayfish.

Aufreinigung: Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from C-Terminus of the protein sequence according to NP_060142.3. Genename: TRPM7

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western blot: 0.3-1.0 μg/mL. Approx.150 kDa band observed in Human Brain (Cerebellum)lysates (calculated MW of 210 kDa according to NP_060142.2). The observed molecularweight corresponds to earlier findings in literature with different antibodies. (Ref.3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TRPM7

Target: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Andere Bezeichnung: TRPM7 (TRPM7 Produkte)

Synonyme: cb495 antikoerper, TRPM7 antikoerper, chak antikoerper, chak1 antikoerper, ltrpc7 antikoerper, trp-plik antikoerper, ALSPDC antikoerper, CHAK antikoerper, CHAK1 antikoerper, LTRPC7 antikoerper, TRP-PLIK antikoerper, 2310022G15Rik antikoerper, 4833414K03Rik antikoerper, 5033407O22Rik antikoerper, LTrpC-7 antikoerper, Ltpr7 antikoerper, Ltrpc7 antikoerper, TRPPLIK antikoerper, Chak antikoerper, Trp-plik antikoerper, transient receptor potential cation channel subfamily M member 7 antikoerper, transient receptor potential cation channel, subfamily M, member 7 antikoerper, TRPM7 antikoerper, trpm7 antikoerper, Trpm7 antikoerper

Hintergrund: The TRPM7 (Transient Receptor Protein-PhosphoLipase C-Interacting Kinase) protein is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. TRPM7, however, is unique among the TRP channel proteins because it is bi-functional. It not only controls ion channels but it also acts as a kinase, phosphorylating proteins.Synonyms: CHAK1, Channel-kinase 1, LTRPC7, Long transient receptor potential channel 7, Transient receptor potential cation channel subfamily M member 7

Gen-ID: 54822

NCBI Accession: NP_060142

UniProt: Q96QT4