THRB Antikörper (Isoform 1, Isoform beta-1, N-Term)

Produktnummer ABIN401449

Produktdetails anti-THRB Antikörper

Target: THRB (Thyroid Hormone Receptor, beta (THRB))

Bindungsspezifität: Isoform 1, Isoform beta-1, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts with THRB protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding to a region near the N-terminal of human THRB isoform 1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/200,000 - 1/220,000. Western Blot: 1/500 - 1/2,000. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.66 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu THRB

Target: THRB (Thyroid Hormone Receptor, beta (THRB))

Andere Bezeichnung: THRB / ERBA2 (THRB Produkte)

Synonyme: C-ERBA-2 antikoerper, C-ERBA-BETA antikoerper, ERBA2 antikoerper, GRTH antikoerper, NR1A2 antikoerper, PRTH antikoerper, THR1 antikoerper, THRB1 antikoerper, THRB2 antikoerper, Nr1a2 antikoerper, T3R[b] antikoerper, T3Rbeta antikoerper, Thrb1 antikoerper, Thrb2 antikoerper, c-erbAbeta antikoerper, TR-beta antikoerper, TR[b]1 antikoerper, fj24f03 antikoerper, trb antikoerper, wu:fj24f03 antikoerper, CTR BETA 2 antikoerper, TR-BETA antikoerper, LOC734147 antikoerper, thrb antikoerper, THRB antikoerper, C-erba-beta antikoerper, RATT3REC antikoerper, T3rec antikoerper, TRbeta antikoerper, THR antikoerper, TRbeta1 antikoerper, thyroid hormone receptor beta antikoerper, thyroid hormone receptor, beta antikoerper, thyroid hormone receptor, beta S homeolog antikoerper, thyroid hormone receptor, beta L homeolog antikoerper, THRB antikoerper, Thrb antikoerper, thrb antikoerper, thrb.S antikoerper, thrb.L antikoerper

Hintergrund: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Defects in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH).Synonyms: NR1A2, Nuclear receptor subfamily 1 group A member 2, THR1, Thyroid hormone receptor beta

Gen-ID: 7068

NCBI Accession: NP_000452

UniProt: P10828

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound