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GGA3 Antikörper (AA 400-415)

GGA3 Reaktivität: Human, Orang-Utan, Makake, Schimpanse WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN401317
  • Target Alle GGA3 Antikörper anzeigen
    GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
    Bindungsspezifität
    • 15
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 400-415
    Reaktivität
    • 33
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Orang-Utan, Makake, Schimpanse
    Wirt
    • 26
    • 3
    • 2
    • 2
    Kaninchen
    Klonalität
    • 31
    • 2
    Polyklonal
    Konjugat
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GGA3 Antikörper ist unkonjugiert
    Applikation
    • 27
    • 13
    • 13
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is directed against GGA3 protein.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Chimpanzee, Macaque, Orangutan.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Synthetic peptide corresponding to amino acids 400-415 of Human GGA3
    Isotyp
    IgG
    Top Product
    Discover our top product GGA3 Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000 - 1/50000. Western Blot: 1/500 - 1/3000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.62 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
  • Target
    GGA3 (Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3))
    Andere Bezeichnung
    GGA3 (GGA3 Produkte)
    Synonyme
    C230037M19Rik antikoerper, mKIAA0154 antikoerper, golgi associated, gamma adaptin ear containing, ARF binding protein 3 antikoerper, Gga3 antikoerper, GGA3 antikoerper
    Hintergrund
    GGA3 (also known as ADPribosylation factor binding protein GGA3, Golgilocalized, gamma ear-containing, ARF-binding protein 3, Gamma-adaptin related protein 3) plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. This protein mediates the ARFdependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. GGA1 is a monomeric protein that interacts with SORT1, SORL1, LRP3, GGA binding partner (GGABP) and P200, GGA1 and GGA2 as well as RABEP1, RABGEF1 and type-I membrane proteins M6PR/CD-MPR, IGF2R/CIMPR and BACE1. GGA3 is a ubiquitously expressed membrane-associated protein that is localized to TGN and endosomes. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: ADP-ribosylation factor-binding protein GGA3, Golgi-localized gamma ear-containing ARF-binding protein 3, KIAA0154
    Gen-ID
    23163
    NCBI Accession
    NP_001166174
    UniProt
    Q9NZ52
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