STK10-A Antikörper (pSer482, pSer486, pSer490)

Produktnummer ABIN372704

Produktdetails anti-STK10-A Antikörper

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Bindungsspezifität: pSer482, pSer486, pSer490

Reaktivität: Human, Maus, Zebrafisch (Danio rerio), Xenopus laevis, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK10-A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody recognizes the ~120k PLKK protein phosphorylated at Ser482,486,490.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Mouse, Rat and Zebrafish.
Species reactivity (tested):Xenopus.

Aufreinigung: Sequential Chromatography on phospho- and dephosphopeptide affinity columns.

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho- Ser482,486,490 of Xenopus polo-like kinase kinase (PLKK).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu STK10-A

Target: STK10-A (Serine/threonine Kinase 10 (STK10-A))

Andere Bezeichnung: PLKK1 (STK10-A Produkte)

Synonyme: LOK antikoerper, PRO2729 antikoerper, Gek1 antikoerper, Lok antikoerper, mKIAA4026 antikoerper, zgc:63495 antikoerper, plkk1 antikoerper, stk10 antikoerper, xPlkk1 antikoerper, serine/threonine kinase 10 antikoerper, serine/threonine kinase 10 S homeolog antikoerper, STK10 antikoerper, Stk10 antikoerper, stk10 antikoerper, stk10.S antikoerper

Hintergrund: Considerable evidence indicates that a polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.Synonyms: Polo-like kinase kinase 1, stk10, xPlkk1

Gen-ID: 373731

NCBI Accession: NP_001079164

UniProt: Q9YHC9