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ABCA4 Antikörper

ABCA4 Reaktivität: Human, Maus, Rind (Kuh), Xenopus laevis WB, IHC (fro) Wirt: Maus Monoclonal 3F4 unconjugated
Produktnummer ABIN371821
  • Target Alle ABCA4 Antikörper anzeigen
    ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
    Reaktivität
    • 21
    • 10
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Rind (Kuh), Xenopus laevis
    Wirt
    • 19
    • 5
    • 2
    Maus
    Klonalität
    • 22
    • 4
    Monoklonal
    Konjugat
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ABCA4 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 10
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    This antibody reacts with ABCA4 (Rim Protein).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Bovine, Human, Mouse and Xenopus.
    Produktmerkmale
    Synonyms: ABCR, Stargardt disease protein, ATP-binding cassette sub-family A member 4,Retinal-specific ATP-binding cassette transporter
    Aufreinigung
    Protein G Chromatography.
    Immunogen
    Partially purified bovine 220-kDa disc rim protein.
    Klon
    3F4
    Isotyp
    IgG
    Top Product
    Discover our top product ABCA4 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry: 1/100. Western blotting: 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    10 mM HEPES ( pH 7.5) 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
    Andere Bezeichnung
    ABCA4 (ABCA4 Produkte)
    Synonyme
    ABC10 antikoerper, ABCR antikoerper, ARMD2 antikoerper, CORD3 antikoerper, FFM antikoerper, RMP antikoerper, RP19 antikoerper, STGD antikoerper, STGD1 antikoerper, AW050280 antikoerper, Abc10 antikoerper, Abcr antikoerper, D430003I15Rik antikoerper, RmP antikoerper, abcr antikoerper, ffm antikoerper, rmp antikoerper, rp19 antikoerper, stgd antikoerper, abc10 antikoerper, armd2 antikoerper, cord3 antikoerper, stgd1 antikoerper, zgc:91823 antikoerper, ATP binding cassette subfamily A member 4 antikoerper, ATP-binding cassette, sub-family A (ABC1), member 4 antikoerper, ATP binding cassette subfamily A member 4 L homeolog antikoerper, ATP-binding cassette, sub-family A (ABC1), member 4a antikoerper, ABCA4 antikoerper, Abca4 antikoerper, abca4 antikoerper, abca4.L antikoerper, abca4a antikoerper
    Hintergrund
    ABCA4 (ATP-binding cassette, sub-family A (ABC1), member 4, Rim Protein) is a member of the superfamily of ATP-binding cassette (ABC) transporters (Illing et al., 1997). ABC proteins transport various molecules across extra- and intracellular membranes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essential molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease and are associated with retinitis pigmentosa-19 and age-related macular degeneration (Wiszniewski et al., 2003). Defects in ABCA4 are the cause of Stargardt disease type 1 (STGD1) (Molday et al., 2000). STGD is one of the most frequent causes of macular degeneration in childhood. Defects in ABCA4 are also known to cause fundus flavimaculatus (FFM), age-related macular degeneration type 2 (ARMD2) and cone-rod dystrophy type 3 (CORD3) (Klevering et al., 2005).Synonyms: ABCR, ATP-binding cassette sub-family A member 4, Retinal-specific ATP-binding cassette transporter, Stargardt disease protein
    Gen-ID
    24
    UniProt
    P78363
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