RAP1GAP Antikörper (AA 412-678)

Produktnummer ABIN5542476

Produktdetails anti-RAP1GAP Antikörper

Target: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Bindungsspezifität: AA 412-678

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAP1GAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human RAP1GAP (AA: 412-678) expressed in E. coli.

Klon: 2G7B6

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu RAP1GAP

Target: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Andere Bezeichnung: RAP1GAP (RAP1GAP Produkte)

Synonyme: RAP1GA1 antikoerper, RAP1GAP1 antikoerper, RAP1GAPII antikoerper, RAPGAP antikoerper, 1300019I11Rik antikoerper, 2310004O14Rik antikoerper, AI427470 antikoerper, Rap1ga1 antikoerper, RAP1 antikoerper, RAP1GAP antikoerper, rap1ga1 antikoerper, rap1gap1 antikoerper, rap1gapii antikoerper, rapgap antikoerper, zgc:175180 antikoerper, DKFZp459A114 antikoerper, RAP1 GTPase activating protein antikoerper, Rap1 GTPase-activating protein antikoerper, RAP1 GTPase activating protein 1 antikoerper, RAP1 GTPase activating protein L homeolog antikoerper, Rap1 GTPase-activating protein 1 antikoerper, si:dkey-166d12.2 antikoerper, RAP1GAP antikoerper, Rap1gap antikoerper, RAP1GAP1 antikoerper, rap1gap.L antikoerper, Tsp_09520 antikoerper, rap1gap antikoerper, si:dkey-166d12.2 antikoerper

Hintergrund:

Description: This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Aliases: RAPGAP, RAP1GA1, RAP1GAP1, RAP1GAPII

Molekulargewicht: 73.4 kDa

Gen-ID: 5909

HGNC: 5909