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IRS4 Antikörper (AA 633-647)

Verified IRS4 Reaktivität: Maus WB, ELISA, IF Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN5539610
  • Target Alle IRS4 Antikörper anzeigen
    IRS4 (Insulin Receptor Substrate 4 (IRS4))
    Bindungsspezifität
    • 15
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 633-647
    Reaktivität
    • 31
    • 22
    • 15
    Maus
    Wirt
    • 36
    • 2
    Ziege
    Klonalität
    • 36
    • 2
    Polyklonal
    Konjugat
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser IRS4 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 26
    • 21
    • 10
    • 6
    • 6
    • 4
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Verwendungszweck
    Irs4 (mouse aa633-647)
    Sequenz
    DRGTKERKEA KEVRD
    Kreuzreaktivität
    Maus, Ratte
    Aufreinigung
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Güteklasse
    Verified
    Isotyp
    IgG
    Top Product
    Discover our top product IRS4 Primärantikörper
  • Applikationshinweise

    Western Blot: Approx 150 kDa band observed in Mouse Heart lysates (calculated MW of 130 kDa according to NP_034702.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Schreyer et al, jEndocrinology. 20

    Peptide ELISA: antibody detection limit dilution 1:128000.

    Kommentare

    Immunofluorescence: This product has been successfully used in IF on Mouse: Harriet M Jackson et al, BMC Genomics. 2013 Nov 25,14:831. PMID: 24274089.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Minimize freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Ikink, Boer, Bakker, Hilkens: "IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation." in: Nature communications, Vol. 7, pp. 13567, (2018) (PubMed).

  • Target
    IRS4 (Insulin Receptor Substrate 4 (IRS4))
    Andere Bezeichnung
    Irs4 (IRS4 Produkte)
    Synonyme
    IRS4 antikoerper, irs-4 antikoerper, py160 antikoerper, IRS-4 antikoerper, PY160 antikoerper, irs2 antikoerper, irs2-a antikoerper, insulin receptor substrate 4 antikoerper, insulin receptor substrate 4 S homeolog antikoerper, IRS4 antikoerper, irs4 antikoerper, Irs4 antikoerper, irs4.S antikoerper
    Hintergrund
    Irs4, insulin receptor substrate 4, IRS-4, RP23-415G1.3, phosphoprotein of 160 kDa, pp160
    Gen-ID
    16370, 315350
    NCBI Accession
    NP_034702
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