FLCN Antikörper (C-Term)

Produktnummer ABIN5539359

Produktdetails anti-FLCN Antikörper

Target: FLCN (Folliculin (FLCN))

Bindungsspezifität: AA 505-534, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLCN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FLCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-534 amino acids from the C-terminal region of human FLCN.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

For IHC-P starting dilution is: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu FLCN

Target: FLCN (Folliculin (FLCN))

Andere Bezeichnung: FLCN (FLCN Produkte)

Synonyme: FLCN antikoerper, flcn antikoerper, wu:fe38g11 antikoerper, zgc:136982 antikoerper, AU014660 antikoerper, B430214A04Rik antikoerper, Bhd antikoerper, FLCL antikoerper, BHD antikoerper, folliculin antikoerper, folliculin S homeolog antikoerper, FLCN antikoerper, flcn antikoerper, flcn.S antikoerper, Flcn antikoerper

Substanzklasse: Amino Acid

Hintergrund: FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). FLCN may be a tumor suppressor. May be involved in colorectal tumorigenesis. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways.

Molekulargewicht: 64 kDa

Gen-ID: 201163

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization