DEAF1 Antikörper (C-Term)

Produktnummer ABIN5539344

Produktdetails anti-DEAF1 Antikörper

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Bindungsspezifität: AA 474-502, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DEAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from the C-terminal region of human DEAF1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DEAF1

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Andere Bezeichnung: DEAF1 (DEAF1 Produkte)

Synonyme: AU042387 antikoerper, C230009B13Rik antikoerper, NUDR antikoerper, SPN antikoerper, ZMYND5 antikoerper, MYND5 antikoerper, spn antikoerper, DEAF1 antikoerper, nudr antikoerper, zmynd5 antikoerper, CG8567 antikoerper, DEAF-1 antikoerper, Deaf-1 antikoerper, Dmel\\CG8567 antikoerper, deaf1 antikoerper, l(3)76BDv antikoerper, deformed epidermal autoregulatory factor 1 (Drosophila) antikoerper, DEAF1, transcription factor antikoerper, DEAF1 transcription factor antikoerper, deformed epidermal autoregulatory factor 1 homolog antikoerper, Deformed epidermal autoregulatory factor-1 antikoerper, Deaf1 antikoerper, DEAF1 antikoerper, LOC509260 antikoerper, deaf1 antikoerper, deaf-1 antikoerper

Hintergrund: Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm.

Molekulargewicht: 59 kDa

Gen-ID: 10522

UniProt: O75398

Pathways: Tube Formation