Transportin 1 Antikörper (N-Term)

Produktnummer ABIN5539321

Produktdetails anti-Transportin 1 Antikörper

Target: Transportin 1 (TNPO1)

Bindungsspezifität: AA 47-74, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transportin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-74 amino acids from the N-terminal region of human TNPO1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Transportin 1

Target: Transportin 1 (TNPO1)

Andere Bezeichnung: TNPO1 (TNPO1 Produkte)

Synonyme: IPO2 antikoerper, KPNB2 antikoerper, MIP antikoerper, MIP1 antikoerper, TRN antikoerper, TNPO1 antikoerper, AU021749 antikoerper, D13Ertd688e antikoerper, Kpnb2 antikoerper, ATTRN1 antikoerper, F12A24.13 antikoerper, F12A24_13 antikoerper, TRANSPORTIN 1 antikoerper, transportin 1 antikoerper, DKFZp469O204 antikoerper, transportin 1 antikoerper, transportin-1 antikoerper, transportin 1 S homeolog antikoerper, TNPO1 antikoerper, LOC738932 antikoerper, tnpo1 antikoerper, Tnpo1 antikoerper, tnpo1.S antikoerper, TRN1 antikoerper

Hintergrund: TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.

Molekulargewicht: 102 kDa

Gen-ID: 3842

UniProt: Q92973

Pathways: PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events