MYSM1 Antikörper (N-Term)

Produktnummer ABIN5538020

Produktdetails anti-MYSM1 Antikörper

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Bindungsspezifität: AA 111-139, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYSM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MYSM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human MYSM1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu MYSM1

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Andere Bezeichnung: MYSM1 (MYSM1 Produkte)

Synonyme: 2A-DUB antikoerper, 2ADUB antikoerper, RP4-592A1.1 antikoerper, C130067A03Rik antikoerper, C530050H10Rik antikoerper, RGD1311787 antikoerper, 2adub antikoerper, Myb like, SWIRM and MPN domains 1 antikoerper, myb-like, SWIRM and MPN domains 1 antikoerper, Myb like, SWIRM and MPN domains 1 L homeolog antikoerper, MYSM1 antikoerper, Mysm1 antikoerper, mysm1.L antikoerper

Hintergrund: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Molekulargewicht: 95 kDa

Gen-ID: 114803

UniProt: Q5VVJ2

Pathways: Chromatin Binding