MMS19 Antikörper (AA 411-437)

Produktnummer ABIN5537935

Produktdetails anti-MMS19 Antikörper

Target: MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))

Bindungsspezifität: AA 411-437

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMS19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MMS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 411-437 amino acids from the Central region of human MMS19.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu MMS19

Target: MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))

Andere Bezeichnung: MMS19 (MMS19 Produkte)

Synonyme: MET18 antikoerper, MMS19L antikoerper, hMMS19 antikoerper, 2410001K24Rik antikoerper, 2610042O15Rik antikoerper, AI316855 antikoerper, C79368 antikoerper, C86341 antikoerper, Mms19l antikoerper, mms19 antikoerper, mms19l antikoerper, MMS19 homolog, cytosolic iron-sulfur assembly component antikoerper, MMS19 (MET18 S. cerevisiae) antikoerper, MMS19 homolog, cytosolic iron-sulfur assembly component L homeolog antikoerper, MMS19 antikoerper, Mms19 antikoerper, mms19.L antikoerper

Hintergrund: MMS19 may play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types.

Molekulargewicht: 113 kDa

Gen-ID: 64210

UniProt: Q96T76

Pathways: Nuclear Hormone Receptor Binding