Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SOS1 Antikörper (AA 934-962)

SOS1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5537593
  • Target Alle SOS1 Antikörper anzeigen
    SOS1 (Son of Sevenless Homolog 1 (SOS1))
    Bindungsspezifität
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 934-962
    Reaktivität
    • 26
    • 12
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 17
    • 11
    • 1
    Kaninchen
    Klonalität
    • 18
    • 11
    Polyklonal
    Konjugat
    • 26
    • 1
    • 1
    • 1
    Dieser SOS1 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 14
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SOS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 934-962 amino acids from the Central region of human SOS1.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SOS1 Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SOS1 (Son of Sevenless Homolog 1 (SOS1))
    Andere Bezeichnung
    SOS1 (SOS1 Produkte)
    Synonyme
    GF1 antikoerper, GGF1 antikoerper, GINGF antikoerper, HGF antikoerper, NS4 antikoerper, 4430401P03Rik antikoerper, 9630010N06 antikoerper, AI449023 antikoerper, SOS Ras/Rac guanine nucleotide exchange factor 1 antikoerper, son of sevenless homolog 1 (Drosophila) antikoerper, SOS1 antikoerper, Sos1 antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    Son of Sevenless 1 protein is an activator of ras proteins by stimulating the exchange of GDP for GTP on ras. Murine Son of Sevenless proteins have been shown to form a complex with activated EGF receptor, coupling tyrosine kinases to ras proteins. The SOS gene was originally isolated in Drosophila. Two mammalian homologues (mSOS1 and mSOS2) have been isolated from a mouse cDNA library and are expressed in a variety of mouse embryo and adult tissues. Human SOS1 and SOS2 homologs have also been isolated. The two mouse homologs are approximately 70 % identical in composition. The mammalian SOS1 protein has a highly specific guanine nucleotide exchange activity towards p21ras. In epidermal growth factor stimulated cells, SOS1 interacts with SH3 domains of GRB2 and binds via SH2 domain to tyrosine 1068 of activated Epidermal Growth Factor receptor.
    Molekulargewicht
    152 kDa
    Gen-ID
    6654
    UniProt
    Q07889
    Pathways
    RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Sie sind hier:
Kundenservice