RFC2 Antikörper (N-Term)

Produktnummer ABIN5537451

Produktdetails anti-RFC2 Antikörper

Target: RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))

Bindungsspezifität: AA 17-46, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This RFC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human RFC2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RFC2

Target: RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))

Andere Bezeichnung: RFC2 (RFC2 Produkte)

Synonyme: 2610008M13Rik antikoerper, 40kDa antikoerper, AI326953 antikoerper, Recc2 antikoerper, RFC40 antikoerper, replication factor C subunit 2 antikoerper, replication factor C (activator 1) 2 antikoerper, LOC100231971 antikoerper, RFC2 antikoerper, Rfc2 antikoerper

Hintergrund: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. RFC2 is the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of RFC2 gene has been associated with Williams syndrome.

Molekulargewicht: 39 kDa

Gen-ID: 5982

UniProt: P35250

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA