COX7A2L Antikörper (AA 37-65)

Produktnummer ABIN5536882

Produktdetails anti-COX7A2L Antikörper

Target: COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))

Bindungsspezifität: AA 37-65

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX7A2L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COX7A2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the Central region of human COX7A2L.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu COX7A2L

Target: COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))

Andere Bezeichnung: COX7A2L (COX7A2L Produkte)

Synonyme: COX7AR antikoerper, COX7RP antikoerper, EB1 antikoerper, SIG81 antikoerper, SIG-81 antikoerper, Silg81 antikoerper, cytochrome c oxidase subunit 7A2 like antikoerper, cytochrome c oxidase subunit VIIa polypeptide 2-like antikoerper, COX7A2L antikoerper, Cox7a2l antikoerper

Hintergrund: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.

Molekulargewicht: 13 kDa

Gen-ID: 9167

UniProt: O14548