LRPPRC Antikörper (AA 1203-1236)

Produktnummer ABIN5536608

Produktdetails anti-LRPPRC Antikörper

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Bindungsspezifität: AA 1203-1236

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRPPRC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LRPPRC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1203-1236 amino acids from human LRPPRC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Andere Bezeichnung: LRPPRC (LRPPRC Produkte)

Synonyme: CLONE-23970 antikoerper, GP130 antikoerper, LRP130 antikoerper, LSFC antikoerper, Lrp157 antikoerper, 3110001K13Rik antikoerper, C76645 antikoerper, Gp130 antikoerper, Lrp130 antikoerper, Lsfc antikoerper, leucine rich pentatricopeptide repeat containing antikoerper, leucine-rich pentatricopeptide repeat containing antikoerper, leucine-rich PPR-motif containing antikoerper, LRPPRC antikoerper, Lrpprc antikoerper

Hintergrund: May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

Molekulargewicht: 158 kDa

Gen-ID: 10128

UniProt: P42704