This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human RGS1.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1R20 antikoerper, BL34 antikoerper, IER1 antikoerper, IR20 antikoerper, RGS1 antikoerper, 1r20 antikoerper, bl34 antikoerper, ier1 antikoerper, ir20 antikoerper, regulator of G protein signaling 1 antikoerper, regulator of G-protein signaling 1 antikoerper, regulator of G-protein signaling 1 S homeolog antikoerper, Regulator of G-protein signaling 1 antikoerper, RGS1 antikoerper, Rgs1 antikoerper, rgs1.S antikoerper, rgs1 antikoerper
Hintergrund
RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.