GSTM1 Antikörper (C-Term)

Produktnummer ABIN5536199

Produktdetails anti-GSTM1 Antikörper

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Bindungsspezifität: AA 184-211, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-211 amino acids from the C-terminal region of human GSTM1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GSTM1

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Andere Bezeichnung: GSTM1 (GSTM1 Produkte)

Synonyme: GST1 antikoerper, GSTM1-1 antikoerper, GSTM1a-1a antikoerper, GSTM1b-1b antikoerper, GTH4 antikoerper, GTM1 antikoerper, H-B antikoerper, MU antikoerper, MU-1 antikoerper, GSTA3 antikoerper, Gstb-1 antikoerper, Gstb1 antikoerper, gst-mu antikoerper, gst1 antikoerper, gstm1 antikoerper, gstm2 antikoerper, gth4 antikoerper, gtm1 antikoerper, glutathione S-transferase mu 1 antikoerper, glutathione S-transferase M1 antikoerper, glutathione S-transferase, mu 1 antikoerper, glutathione S-transferase Mu 1 antikoerper, glutathione S-transferase mu 2 (muscle) antikoerper, glutathione S-transferase mu 1 L homeolog antikoerper, GSTM1 antikoerper, Gstm1 antikoerper, LOC100356307 antikoerper, GSTM2 antikoerper, LOC100731426 antikoerper, gstm1.L antikoerper

Hintergrund: GSTM1 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Molekulargewicht: 26 kDa

Gen-ID: 2944

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity