TDG Antikörper (N-Term)

Produktnummer ABIN5536146

Produktdetails anti-TDG Antikörper

Target: TDG (Thymine-DNA Glycosylase (TDG))

Bindungsspezifität: AA 81-110, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TDG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This TDG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human TDG.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TDG

Target: TDG (Thymine-DNA Glycosylase (TDG))

Andere Bezeichnung: TDG (TDG Produkte)

Synonyme: 5-MCDG antikoerper, wu:fb44b11 antikoerper, zgc:110622 antikoerper, MGC82456 antikoerper, MGC89441 antikoerper, E130317C12Rik antikoerper, JZA-3 antikoerper, Jza1 antikoerper, hTDG antikoerper, thymine DNA glycosylase antikoerper, thymine DNA glycosylase, tandem duplicate 1 antikoerper, putative g/t mismatch-specific thymine DNA glycosylase antikoerper, G/T mismatch-specific thymine DNA glycosylase antikoerper, thymine DNA glycosylase S homeolog antikoerper, thymine-DNA glycosylase antikoerper, TDG antikoerper, tdg.1 antikoerper, Smp_149220 antikoerper, Tsp_05734 antikoerper, tdg.S antikoerper, tdg antikoerper, Tdg antikoerper

Hintergrund: The protein TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.

Molekulargewicht: 46 kDa

Gen-ID: 6996

UniProt: Q13569

Pathways: DNA Reparatur, Chromatin Binding