This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This EDEM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-802 amino acids from the C-terminal region of human EDEM3.
EDEM3
Reaktivität: Ratte
IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
Alexa Fluor 647
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.43 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
RGD1561496 antikoerper, C1orf22 antikoerper, 2310050N11Rik antikoerper, ER degradation enhancing alpha-mannosidase like protein 3 antikoerper, ER degradation enhancer, mannosidase alpha-like 3 L homeolog antikoerper, ER degradation enhancer, mannosidase alpha-like 3 antikoerper, Edem3 antikoerper, EDEM3 antikoerper, edem3.L antikoerper, edem3 antikoerper
Hintergrund
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).