CHM Antikörper (AA 292-320)

Produktnummer ABIN5535605

Produktdetails anti-CHM Antikörper

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Bindungsspezifität: AA 292-320

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CHM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-320 amino acids from the Central region of human CHM.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.27 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CHM

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Andere Bezeichnung: CHM (CHM Produkte)

Synonyme: CHM antikoerper, REP1 antikoerper, DXS540 antikoerper, GGTA antikoerper, HSD-32 antikoerper, REP-1 antikoerper, TCD antikoerper, DKFZp459K2154 antikoerper, tcd antikoerper, ggta antikoerper, rep-1 antikoerper, dxs540 antikoerper, hsd-32 antikoerper, MGC68578 antikoerper, Rep-1 antikoerper, chm antikoerper, chm-a antikoerper, chm-b antikoerper, chml antikoerper, CHM, Rab escort protein 1 antikoerper, choroideremia (Rab escort protein 1) antikoerper, choroideremia (Rab escort protein 1) L homeolog antikoerper, choroidermia (RAB escort protein 1) antikoerper, choroideremia (Rab escort protein 1) S homeolog antikoerper, CHM antikoerper, chm antikoerper, chm.L antikoerper, Chm antikoerper, chm.S antikoerper

Hintergrund: This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 73 kDa

Gen-ID: 1121

UniProt: P24386

Pathways: Sensory Perception of Sound