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PDGFRB Antikörper (N-Term)

PDGFRB Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5535580
  • Target Alle PDGFRB Antikörper anzeigen
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Bindungsspezifität
    • 24
    • 22
    • 22
    • 18
    • 15
    • 8
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-72, N-Term
    Reaktivität
    • 220
    • 102
    • 82
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 184
    • 42
    • 6
    • 2
    Kaninchen
    Klonalität
    • 171
    • 63
    Polyklonal
    Konjugat
    • 116
    • 13
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Dieser PDGFRB Antikörper ist unkonjugiert
    Applikation
    • 162
    • 81
    • 54
    • 54
    • 53
    • 36
    • 33
    • 27
    • 16
    • 13
    • 12
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This PDGFRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-72 amino acids from the N-terminal region of human PDGFRB.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PDGFRB Primärantikörper
  • Applikationshinweise
    For IHC-P starting dilution is: 1:10~50

    For IF starting dilution is: 1:10~50

    For FACS starting dilution is: 1:10~50

    For WB starting dilution is: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Andere Bezeichnung
    PDGFRB (PDGFRB Produkte)
    Synonyme
    AI528809 antikoerper, CD140b antikoerper, PDGFR-1 antikoerper, Pdgfr antikoerper, CD140B antikoerper, IBGC4 antikoerper, JTK12 antikoerper, PDGFR antikoerper, PDGFR1 antikoerper, platelet derived growth factor receptor, beta polypeptide antikoerper, platelet derived growth factor receptor beta antikoerper, Pdgfrb antikoerper, PDGFRB antikoerper
    Hintergrund
    PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.
    Molekulargewicht
    124 kDa
    Gen-ID
    5159
    UniProt
    P09619
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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