This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This POLR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human POLR1B.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
POLR1B
(Polymerase (RNA) I Polypeptide B, 128kDa (POLR1B))
RPOL-1l antikoerper, MGC68946 antikoerper, 128kDa antikoerper, D630020H17Rik antikoerper, RPA116 antikoerper, RPA135 antikoerper, RPA2 antikoerper, Rpo1-2 antikoerper, RNA polymerase I subunit B antikoerper, polymerase (RNA) I polypeptide B L homeolog antikoerper, polymerase (RNA) I polypeptide B, 128kDa antikoerper, polymerase (RNA) I polypeptide B antikoerper, DNA-directed RNA polymerase I subunit RPA2 antikoerper, POLR1B antikoerper, polr1b.L antikoerper, polr1b antikoerper, LOC100563266 antikoerper, LOC100634236 antikoerper, Polr1b antikoerper
Hintergrund
Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).