This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This POLR2E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human POLR2E.
POLR2E
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
POLR2E
(Polymerase (RNA) II (DNA Directed) Polypeptide E, 25kDa (POLR2E))
MGC68604 antikoerper, polr2e antikoerper, wu:fk97g10 antikoerper, zgc:101098 antikoerper, 2410021N14Rik antikoerper, 25kDa antikoerper, AW208866 antikoerper, RPB5 antikoerper, XAP4 antikoerper, RPABC1 antikoerper, hRPB25 antikoerper, hsRPB5 antikoerper, polymerase (RNA) II (DNA directed) polypeptide E, 25kDa S homeolog antikoerper, RNA polymerase II subunit E antikoerper, polymerase (RNA) II (DNA directed) polypeptide E, b antikoerper, polymerase (RNA) II (DNA directed) polypeptide E, 25kDa antikoerper, polymerase (RNA) II (DNA directed) polypeptide E antikoerper, DNA-directed RNA polymerases I, II, and III subunit RPABC1 antikoerper, polr2e.S antikoerper, POLR2E antikoerper, polr2eb antikoerper, polr2e antikoerper, Polr2e antikoerper, rpb-5 antikoerper
Hintergrund
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.