This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This WNT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-201 amino acids from the Central region of human WNT6.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
WNT6
(Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))
WNT6 antikoerper, si:dkey-31m21.2 antikoerper, Wnt6 antikoerper, AA409270 antikoerper, Wnt-6 antikoerper, Xwnt-6 antikoerper, wnt-6 antikoerper, wnt6-A antikoerper, xWnt6 antikoerper, Wnt family member 6 antikoerper, wingless-type MMTV integration site family, member 6b antikoerper, wingless-type MMTV integration site family, member 6 antikoerper, Wnt family member 6 S homeolog antikoerper, WNT6 antikoerper, Wnt6 antikoerper, wnt6b antikoerper, wnt6.S antikoerper
Hintergrund
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.