UBE2D1 Antikörper (C-Term)

Produktnummer ABIN5534798

Produktdetails anti-UBE2D1 Antikörper

Target: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Bindungsspezifität: AA 111-140, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This UBE2D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the C-terminal region of human UBE2D1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For IHC-P starting dilution is: 1:100

For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu UBE2D1

Target: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Andere Bezeichnung: UBE2D1 (UBE2D1 Produkte)

Synonyme: E2(17)KB1 antikoerper, SFT antikoerper, UBC4/5 antikoerper, UBCH5 antikoerper, UBCH5A antikoerper, ube2d1 antikoerper, wu:fc16h06 antikoerper, zgc:73096 antikoerper, e2(17)kb1 antikoerper, sft antikoerper, ubc4/5 antikoerper, ubch5 antikoerper, ubch5a antikoerper, ubiquitin conjugating enzyme E2 D1 antikoerper, ubiquitin-conjugating enzyme E2D 1 antikoerper, ubiquitin-conjugating enzyme E2D 1b antikoerper, ubiquitin conjugating enzyme E2 D1 S homeolog antikoerper, UBE2D1 antikoerper, Ube2d1 antikoerper, ube2d1b antikoerper, ube2d1.S antikoerper, ube2d1 antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

Molekulargewicht: 17 kDa

Gen-ID: 7321

UniProt: P51668

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades