TGIF1 Antikörper (AA 208-237)

Produktnummer ABIN5534742

Produktdetails anti-TGIF1 Antikörper

Target: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Bindungsspezifität: AA 208-237

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGIF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This TGIF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human TGIF.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TGIF1

Target: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Andere Bezeichnung: TGIF (TGIF1 Produkte)

Synonyme: HPE4 antikoerper, TGIF antikoerper, AA959811 antikoerper, AI462167 antikoerper, Tgif antikoerper, Tfig antikoerper, fa06h05 antikoerper, fb33g11 antikoerper, zgc:55852 antikoerper, wu:fa06h05 antikoerper, wu:fb33g11 antikoerper, hpe4 antikoerper, tgif antikoerper, tgif1 antikoerper, TGFB induced factor homeobox 1 antikoerper, TGFB-induced factor homeobox 1 antikoerper, TGFB induced factor homeobox 1 S homeolog antikoerper, TGIF1 antikoerper, Tgif1 antikoerper, tgif1 antikoerper, tgif1.S antikoerper

Hintergrund: TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.

Molekulargewicht: 43 kDa

Gen-ID: 7050

UniProt: Q15583

Pathways: Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation