SPPL2A Antikörper (N-Term)

Produktnummer ABIN5534701

Produktdetails anti-SPPL2A Antikörper

Target: SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))

Bindungsspezifität: AA 108-138, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPPL2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This SPPL2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-138 amino acids from the N-terminal region of human SPPL2a.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SPPL2A

Target: SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))

Andere Bezeichnung: SPPL2a (SPPL2A Produkte)

Synonyme: RGD1563001 antikoerper, SPPL2A antikoerper, LOC453430 antikoerper, LOC100231183 antikoerper, IMP3 antikoerper, PSL2 antikoerper, 2010106G01Rik antikoerper, C130089K23Rik antikoerper, signal peptide peptidase-like 2A antikoerper, signal peptide peptidase like 2A antikoerper, Signal peptide peptidase-like 2A antikoerper, Sppl2a antikoerper, SPPL2A antikoerper, sppl2a antikoerper, psl2 antikoerper

Hintergrund: By searching sequence databases for homologs of Dictyostelium discoideum Impas, which shares homology with presenilin, followed by PCR of lymphocyte and hippocampus cDNA libraries, Grigorenko et al. (2002) cloned SPPL2a. This protein, which may act as an intramembrane protease, contains an N-terminal protease-associated (PA) domain, several transmembrane regions, a hydrophilic loop, conservative sequences around the first and second aspartate residues, and an invariant PAL motif near the C terminus.

Molekulargewicht: 58 kDa

Gen-ID: 84888

UniProt: Q8TCT8