PDE6A Antikörper (AA 308-336)
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- Target Alle PDE6A Antikörper anzeigen
- PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
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Bindungsspezifität
- AA 308-336
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDE6A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PDE6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-336 amino acids from the Central region of human PDE6A.
- Isotyp
- Ig Fraction
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- Applikationshinweise
- For WB starting dilution is: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
- Andere Bezeichnung
- PDE6A (PDE6A Produkte)
- Synonyme
- si:bz1d10.3 antikoerper, si:rp71-1d10.3 antikoerper, CGPR-A antikoerper, PDEA antikoerper, RP43 antikoerper, Pdea antikoerper, nmf282 antikoerper, phosphodiesterase 6A, cGMP-specific, rod, alpha antikoerper, phosphodiesterase 6A antikoerper, pde6a antikoerper, PDE6A antikoerper, Pde6a antikoerper
- Hintergrund
- This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
- Molekulargewicht
- 100 kDa
- Gen-ID
- 5145
- UniProt
- P16499
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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