Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PDE6A Antikörper (AA 308-336)

PDE6A Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5534630
  • Target Alle PDE6A Antikörper anzeigen
    PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
    Bindungsspezifität
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    AA 308-336
    Reaktivität
    • 25
    • 11
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 25
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 13
    • 3
    • 3
    • 2
    • 2
    • 2
    Dieser PDE6A Antikörper ist unkonjugiert
    Applikation
    • 22
    • 17
    • 9
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PDE6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-336 amino acids from the Central region of human PDE6A.
    Isotyp
    Ig Fraction
  • Applikationshinweise
    For WB starting dilution is: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
    Andere Bezeichnung
    PDE6A (PDE6A Produkte)
    Synonyme
    si:bz1d10.3 antikoerper, si:rp71-1d10.3 antikoerper, CGPR-A antikoerper, PDEA antikoerper, RP43 antikoerper, Pdea antikoerper, nmf282 antikoerper, phosphodiesterase 6A, cGMP-specific, rod, alpha antikoerper, phosphodiesterase 6A antikoerper, pde6a antikoerper, PDE6A antikoerper, Pde6a antikoerper
    Hintergrund
    This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
    Molekulargewicht
    100 kDa
    Gen-ID
    5145
    UniProt
    P16499
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
Sie sind hier:
Kundenservice