PIK3 gamma Antikörper (C-Term)

Produktnummer ABIN5534583

Produktdetails anti-PIK3 gamma Antikörper

Target: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Bindungsspezifität: AA 1041-1070, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3 gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PI3CKG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1041-1070 amino acids from the C-terminal region of human PI3CKG.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PIK3 gamma

Target: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Andere Bezeichnung: PIK3CG (PIK3CG Produkte)

Synonyme: PI3CG antikoerper, PI3K antikoerper, PI3Kgamma antikoerper, PIK3 antikoerper, Pi3k antikoerper, wu:fb15d07 antikoerper, zgc:77033 antikoerper, pi3k antikoerper, 5830428L06Rik antikoerper, p110gamma antikoerper, p120-PI3K antikoerper, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma antikoerper, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma antikoerper, si:rp71-17i16.5 antikoerper, PIK3CG antikoerper, Pik3cg antikoerper, pik3cg antikoerper, si:rp71-17i16.5 antikoerper

Hintergrund: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.

Molekulargewicht: 126 kDa

Gen-ID: 5294

UniProt: P48736

Pathways: PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, TLR Signalweg, Inositol Metabolic Process, Hepatitis C, VEGF Signaling