Der1-Like Domain Family, Member 2 (DERL2) (AA 191-219), (C-Term) Antikörper

Produktnummer ABIN5534196

Produktdetails

Target: Der1-Like Domain Family, Member 2 (DERL2)

Bindungsspezifität: AA 191-219, C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Derl2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the C-terminal region of mouse Derl2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Antigendetails

Target: Der1-Like Domain Family, Member 2 (DERL2)

Andere Bezeichnung: Derl2 (DERL2 Produkte)

Synonyme: F-LAN-1 antikoerper, F-LANa antikoerper, FLANa antikoerper, BC005682 antikoerper, CGI-101 antikoerper, Derlin-2 antikoerper, F-lana antikoerper, Flana antikoerper, RP23-83I13.8 antikoerper, derl2 antikoerper, zgc:110436 antikoerper, CG14899 antikoerper, Cg14899 antikoerper, DER1 antikoerper, Dmel\\CG14899 antikoerper, derlin 2 antikoerper, Der1-like domain family, member 2 antikoerper, derlin-2 antikoerper, derlin-2.1 antikoerper, derlin 2 S homeolog antikoerper, Derlin-2 antikoerper, DERL2 antikoerper, Derl2 antikoerper, derl2 antikoerper, PVX_117040 antikoerper, CpipJ_CPIJ012528 antikoerper, MCYG_03163 antikoerper, VDBG_06959 antikoerper, LOAG_05811 antikoerper, MGYG_00329 antikoerper, derl2.S antikoerper, Der-2 antikoerper

Hintergrund: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate (By similarity).

Molekulargewicht: 28 kDa

Gen-ID: 116891

UniProt: Q8BNI4

Pathways: ER-Nucleus Signaling, Feeding Behaviour