Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogen
This P450R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 462-488 amino acids from the Central region of human P450R.
CYP2B6
Reaktivität: Human, Maus
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
2 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
CYP2B6
(Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6))
CPB6 antikoerper, CYP2B antikoerper, CYP2B7 antikoerper, CYP2B7P antikoerper, CYPIIB6 antikoerper, EFVM antikoerper, IIB1 antikoerper, P450 antikoerper, CPF3 antikoerper, CYP4F antikoerper, LTB4H antikoerper, CYP2B30 antikoerper, CYP2B11 antikoerper, CYPIIB11 antikoerper, 21-OH antikoerper, 21OH antikoerper, 21OHA antikoerper, 21OHB antikoerper, CYP21OH-A antikoerper, Cyp21 antikoerper, Cyp21-ps1 antikoerper, Cyp21B antikoerper, Cyp21a2-ps antikoerper, Cyp21a2ps antikoerper, Oh21-1 antikoerper, Oh21-2 antikoerper, CYP2B6 antikoerper, cytochrome P450 family 2 subfamily B member 6 antikoerper, cytochrome P450 family 4 subfamily F member 3 antikoerper, cytochrome P450, family 2, subfamily B, polypeptide 6 antikoerper, cytochrome P450 family 2 subfamily B member 6 L homeolog antikoerper, cytochrome P450 2B11 antikoerper, cytochrome P450, family 21, subfamily a, polypeptide 1 antikoerper, cytochrome P450 subfamily 2B antikoerper, cytochrome P450 2B11-like antikoerper, CYP2B6 antikoerper, CYP4F3 antikoerper, cyp2b6.L antikoerper, Cyp21a1 antikoerper, LOC100068603 antikoerper
Hintergrund
P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.