GJB4 Antikörper (N-Term)

Produktnummer ABIN5534073

Produktdetails anti-GJB4 Antikörper

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Bindungsspezifität: AA 90-120, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This Connexin 30.3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the N-terminal region of human Connexin 30.3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.1 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GJB4

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Andere Bezeichnung: Connexin 30.3 (GJB4 Produkte)

Synonyme: GJB4 antikoerper, Cnx30.3 antikoerper, Cx30.3 antikoerper, Gjb-4 antikoerper, CX30.3 antikoerper, EKV antikoerper, gap junction protein beta 4 antikoerper, gap junction protein, beta 4 antikoerper, GJB4 antikoerper, Gjb4 antikoerper

Hintergrund: Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.

Molekulargewicht: 30 kDa

Gen-ID: 127534

UniProt: Q9NTQ9