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CPT1C Antikörper (C-Term)

CPT1C Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5533976
  • Target Alle CPT1C Antikörper anzeigen
    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
    Bindungsspezifität
    • 15
    • 12
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 752-782, C-Term
    Reaktivität
    • 53
    • 6
    • 3
    Human
    Wirt
    • 54
    • 1
    • 1
    Kaninchen
    Klonalität
    • 55
    • 1
    Polyklonal
    Konjugat
    • 21
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CPT1C Antikörper ist unkonjugiert
    Applikation
    • 47
    • 36
    • 13
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CPT1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 752-782 amino acids from the C-terminal region of human CPT1C.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CPT1C Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:1000

    For FACS starting dilution is: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.3 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
    Andere Bezeichnung
    CPT1C (CPT1C Produkte)
    Synonyme
    6530437J22Rik antikoerper, 9630004I06Rik antikoerper, CATL1 antikoerper, CPT1-B antikoerper, CPT1P antikoerper, CPTI-B antikoerper, CPTIC antikoerper, CPT IC antikoerper, carnitine palmitoyltransferase 1c antikoerper, carnitine palmitoyltransferase 1C antikoerper, Cpt1c antikoerper, CPT1C antikoerper
    Hintergrund
    The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.
    Molekulargewicht
    91 kDa
    Gen-ID
    126129
    UniProt
    Q8TCG5
    Pathways
    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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