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COPS7B Antikörper (AA 61-95)

COPS7B Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5533967
  • Target Alle COPS7B Antikörper anzeigen
    COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
    Bindungsspezifität
    • 15
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 61-95
    Reaktivität
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 25
    • 2
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COPS7B Antikörper ist unkonjugiert
    Applikation
    • 23
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This COPS7B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 61-95 amino acids from human COPS7B.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product COPS7B Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
    Andere Bezeichnung
    COPS7B (COPS7B Produkte)
    Synonyme
    MGC114836 antikoerper, D1Wsu66e antikoerper, E130114M23 antikoerper, CSN7B antikoerper, COP9 signalosome subunit 7B antikoerper, COP9 signalosome subunit 7B S homeolog antikoerper, Cops7b antikoerper, COPS7B antikoerper, cops7b.S antikoerper
    Hintergrund
    Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
    Molekulargewicht
    30 kDa
    Gen-ID
    64708
    UniProt
    Q9H9Q2
    Pathways
    Zellzyklus
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