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PRKAG3 Antikörper (AA 148-178)

PRKAG3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5533704
  • Target Alle PRKAG3 Antikörper anzeigen
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 148-178
    Reaktivität
    • 63
    • 12
    • 1
    Human, Maus
    Wirt
    • 55
    • 9
    • 1
    Kaninchen
    Klonalität
    • 56
    • 9
    Polyklonal
    Konjugat
    • 24
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PRKAG3 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 33
    • 15
    • 13
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This PRKAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-178 amino acids from the Central region of human PRKAG3.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PRKAG3 Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
    Andere Bezeichnung
    PRKAG3 (PRKAG3 Produkte)
    Synonyme
    Ampkg3 antikoerper, prkag3-a antikoerper, PRKAG3 antikoerper, AMPKG3 antikoerper, AMPKg3L antikoerper, AMPKg3S antikoerper, Amkg3 antikoerper, protein kinase AMP-activated non-catalytic subunit gamma 3 antikoerper, protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit antikoerper, Prkag3 antikoerper, PRKAG3 antikoerper, prkag3.S antikoerper, prkag3-b antikoerper
    Hintergrund
    PRKAG3 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
    Molekulargewicht
    54 kDa
    Gen-ID
    53632
    UniProt
    Q9UGI9
    Pathways
    AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effekt
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