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Myomesin 1 Antikörper (AA 904-933)

MYOM1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5533533
  • Target Alle Myomesin 1 (MYOM1) Antikörper anzeigen
    Myomesin 1 (MYOM1)
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 904-933
    Reaktivität
    • 38
    • 20
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 1
    Kaninchen
    Klonalität
    • 37
    • 1
    Polyklonal
    Konjugat
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Myomesin 1 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 19
    • 18
    • 13
    • 5
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MYOM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 904-933 amino acids from the Central region of human MYOM1.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MYOM1 Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    Myomesin 1 (MYOM1)
    Andere Bezeichnung
    MYOM1 (MYOM1 Produkte)
    Synonyme
    SKELEMIN antikoerper, D430047A17Rik antikoerper, myomesin 1 antikoerper, myomesin 1, 185kDa antikoerper, MYOM1 antikoerper, Myom1 antikoerper
    Hintergrund
    The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50 % sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Molekulargewicht
    188 kDa
    Gen-ID
    8736
    UniProt
    P52179
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