RCAN1 Antikörper (N-Term)

Produktnummer ABIN5533131

Produktdetails anti-RCAN1 Antikörper

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Bindungsspezifität: AA 41-68, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human RCAN1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.43 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Andere Bezeichnung: RCAN1 (RCAN1 Produkte)

Synonyme: ADAPT78 antikoerper, CSP1 antikoerper, DSC1 antikoerper, DSCR1 antikoerper, MCIP1 antikoerper, RCN1 antikoerper, RCAN1 antikoerper, 2410048A02Rik antikoerper, AA408855 antikoerper, AI429645 antikoerper, AL024459 antikoerper, AV028423 antikoerper, Adapt78 antikoerper, CALP1L antikoerper, Dscr1 antikoerper, Mcip1 antikoerper, dscr1 antikoerper, rcan1 antikoerper, wu:fr92c05 antikoerper, adapt78 antikoerper, csp1 antikoerper, dsc1 antikoerper, mcip1 antikoerper, MGC53636 antikoerper, rcn1 antikoerper, MGC69428 antikoerper, regulator of calcineurin 1 antikoerper, regulator of calcineurin 1b antikoerper, regulator of calcineurin 1 L homeolog antikoerper, Down syndrome critical region gene 1 antikoerper, RCAN1 antikoerper, Rcan1 antikoerper, rcan1b antikoerper, rcan1.L antikoerper, dscr1 antikoerper, rcan1 antikoerper

Hintergrund: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

Molekulargewicht: 28 kDa

Gen-ID: 1827

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development