Kv1.4 Antikörper (C-Term)

Produktnummer ABIN5533118

Produktdetails anti-Kv1.4 Antikörper

Target: Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))

Bindungsspezifität: AA 591-619, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kv1.4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KCNA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 591-619 amino acids from the C-terminal region of human KCNA4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Kv1.4

Target: Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))

Andere Bezeichnung: KCNA4 (KCNA4 Produkte)

Synonyme: KV1.4 antikoerper, KCNA4 antikoerper, Kv1.4 antikoerper, DKFZp459N0126 antikoerper, KCHAN antikoerper, Kv4 antikoerper, RHK1 antikoerper, RK3 antikoerper, HBK4 antikoerper, HK1 antikoerper, HPCN2 antikoerper, HUKII antikoerper, KCNA4L antikoerper, KCNA8 antikoerper, PCN2 antikoerper, potassium voltage-gated channel subfamily A member 4 antikoerper, potassium voltage-gated channel subfamily A member 4 S homeolog antikoerper, potassium voltage-gated channel, shaker-related subfamily, member 4 antikoerper, KCNA4 antikoerper, LOC100622932 antikoerper, kcna4.S antikoerper, Kcna4 antikoerper

Hintergrund: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influnce the duration of cardiac action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.

Molekulargewicht: 73 kDa

Gen-ID: 3739

UniProt: P22459