This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ASAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human ASAP1.
ASAP1
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
ASAP1
(ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))
AV239055 antikoerper, DEF-1 antikoerper, Ddef1 antikoerper, PAP antikoerper, mKIAA1249 antikoerper, s19 antikoerper, AMAP1 antikoerper, CENTB4 antikoerper, DDEF1 antikoerper, PAG2 antikoerper, ZG14P antikoerper, ASAP1 antikoerper, ddef1 antikoerper, Asap1 antikoerper, si:ch211-160i2.3 antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain1 antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 antikoerper, toxic extracellular endopeptidase antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog antikoerper, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a antikoerper, Asap1 antikoerper, ASAP1 antikoerper, asaP1 antikoerper, asap1 antikoerper, asap1.L antikoerper, asap1a antikoerper
Hintergrund
Possesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity).