RANGAP1 Antikörper (N-Term)

Produktnummer ABIN5532010

Produktdetails anti-RANGAP1 Antikörper

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Bindungsspezifität: AA 20-49, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RANGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RANGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RANGAP1

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Andere Bezeichnung: RANGAP1 (RANGAP1 Produkte)

Synonyme: Fug1 antikoerper, RANGAP antikoerper, SD antikoerper, ATRANGAP1 antikoerper, RAN GTPASE-ACTIVATING PROTEIN 1 antikoerper, RAN GTPase activating protein 1 antikoerper, RanGAP1 antikoerper, fug1 antikoerper, rangap1b antikoerper, rna1p antikoerper, C79654 antikoerper, mKIAA1835 antikoerper, rangap1 antikoerper, rangap1a antikoerper, Protein rna1 antikoerper, CG9999 antikoerper, CT28175 antikoerper, Dmel\CG9999 antikoerper, RGP1_DROME antikoerper, Ran antikoerper, RanGAP antikoerper, RanGap antikoerper, RanGap1 antikoerper, Scl antikoerper, Sd antikoerper, Sd-RanGAP antikoerper, Sd-RanGap antikoerper, dRanGAP antikoerper, ranGAP antikoerper, ranGap antikoerper, rangap antikoerper, zgc:154097 antikoerper, Ran GTPase activating protein 1 antikoerper, RAN GTPase activating protein 1 antikoerper, ran GTPase activating protein 1 antikoerper, Ran GTPase activating protein 1 S homeolog antikoerper, Ran GTPase activating protein 1 L homeolog antikoerper, Ran GAP Rna1 antikoerper, Ran GTPase activating protein antikoerper, RAN GTPase activating protein 1a antikoerper, RANGAP1 antikoerper, TERG_02084 antikoerper, rangap1.S antikoerper, Rangap1 antikoerper, rangap1.L antikoerper, rna1 antikoerper, RanGAP antikoerper, rangap1a antikoerper

Hintergrund: RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88 % identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

Molekulargewicht: 64 kDa

Gen-ID: 5905

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus