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EBP Antikörper (C-Term)

EBP Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5531917
  • Target Alle EBP Antikörper anzeigen
    EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    AA 201-230, C-Term
    Reaktivität
    • 41
    • 13
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    Kaninchen
    Klonalität
    • 42
    Polyklonal
    Konjugat
    • 16
    • 6
    • 6
    • 6
    • 4
    • 4
    Dieser EBP Antikörper ist unkonjugiert
    Applikation
    • 34
    • 33
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This EBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the C-terminal region of human EBP.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product EBP Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.45 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
    Andere Bezeichnung
    EBP (EBP Produkte)
    Synonyme
    cdpx2 antikoerper, cho2 antikoerper, cpx antikoerper, cpxd antikoerper, zgc:91895 antikoerper, CDPX2 antikoerper, CHO2 antikoerper, CPX antikoerper, CPXD antikoerper, AI255399 antikoerper, Pabp antikoerper, Td antikoerper, mSI antikoerper, emopamil binding protein (sterol isomerase) antikoerper, emopamil binding protein (sterol isomerase) L homeolog antikoerper, phenylalkylamine Ca2+ antagonist (emopamil) binding protein antikoerper, Ebp antikoerper, ebp.L antikoerper, ebp antikoerper, EBP antikoerper
    Hintergrund
    The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23 % ) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).
    Molekulargewicht
    26 kDa
    Gen-ID
    10682
    UniProt
    Q15125
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