This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PADI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-586 amino acids from the C-terminal region of human PADI2.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
PADI2
(Peptidyl Arginine Deiminase, Type II (PADI2))
PADI2 antikoerper, PAD-H19 antikoerper, PAD2 antikoerper, PDI2 antikoerper, Pdi antikoerper, Pdi2 antikoerper, mKIAA0994 antikoerper, peptidyl arginine deiminase 2 antikoerper, peptidyl arginine deiminase, type II antikoerper, protein-arginine deiminase type-2 antikoerper, peptidyl arginine deiminase, type II S homeolog antikoerper, PADI2 antikoerper, padi2 antikoerper, LOC100357368 antikoerper, padi2.S antikoerper, Padi2 antikoerper
Hintergrund
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq].