DUSP4 Antikörper (C-Term)

Produktnummer ABIN5531048

Produktdetails anti-DUSP4 Antikörper

Target: DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

Bindungsspezifität: AA 331-361, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This DUSP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human DUSP4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DUSP4

Target: DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

Andere Bezeichnung: DUSP4 (DUSP4 Produkte)

Synonyme: zgc:55423 antikoerper, DUSP4 antikoerper, typ antikoerper, hvh2 antikoerper, mkp2 antikoerper, mkp-2 antikoerper, MGC131045 antikoerper, HVH2 antikoerper, MKP-2 antikoerper, MKP2 antikoerper, TYP antikoerper, 2700078F24Rik antikoerper, AI844617 antikoerper, BB104621 antikoerper, E130306H24Rik antikoerper, Mkp-2 antikoerper, Mkp2 antikoerper, dual specificity phosphatase 4 antikoerper, dual specificity phosphatase 4 S homeolog antikoerper, dusp4 antikoerper, DUSP4 antikoerper, dusp4.S antikoerper, Dusp4 antikoerper

Hintergrund: DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.

Molekulargewicht: 43 kDa

Gen-ID: 1846

UniProt: Q13115

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades