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Dual Specificity Phosphatase 3 (DUSP3) (AA 157-185), (C-Term) Antikörper

DUSP3 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5531047
  • Target Alle Dual Specificity Phosphatase 3 (DUSP3) Antikörper anzeigen
    Dual Specificity Phosphatase 3 (DUSP3)
    Bindungsspezifität
    • 15
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 157-185, C-Term
    Reaktivität
    • 41
    • 21
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 52
    • 7
    Kaninchen
    Klonalität
    • 52
    • 7
    Polyklonal
    Konjugat
    • 27
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 41
    • 23
    • 14
    • 13
    • 13
    • 13
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This DUSP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-185 amino acids from the C-terminal region of human DUSP3.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DUSP3 Primärantikörper
  • Applikationshinweise
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    For FACS starting dilution is: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    Dual Specificity Phosphatase 3 (DUSP3)
    Andere Bezeichnung
    DUSP3 (DUSP3 Produkte)
    Synonyme
    dusp3 antikoerper, si:bz18k17.3 antikoerper, si:rp71-18k17.3 antikoerper, VHR antikoerper, RGD1560049 antikoerper, 2210015O03Rik antikoerper, 5031436O03Rik antikoerper, T-DSP11 antikoerper, dual specificity phosphatase 3 antikoerper, dual specificity phosphatase 3b antikoerper, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) antikoerper, DUSP3 antikoerper, dusp3b antikoerper, Dusp3 antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. The gene for this protein maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer.
    Molekulargewicht
    20 kDa
    Gen-ID
    1845
    UniProt
    P51452
    Pathways
    Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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