DAAM1 Antikörper (C-Term)

Produktnummer ABIN5530990

Produktdetails anti-DAAM1 Antikörper

Target: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Bindungsspezifität: AA 1034-1063, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DAAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1034-1063 amino acids from the C-terminal region of human DAAM1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DAAM1

Target: DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))

Andere Bezeichnung: DAAM1 (DAAM1 Produkte)

Synonyme: 1700066F09Rik antikoerper, 2310028E21Rik antikoerper, AI503486 antikoerper, E130308H01 antikoerper, mKIAA0666 antikoerper, daam-1 antikoerper, xdaam1 antikoerper, daam1 antikoerper, DAAM1 antikoerper, DKFZp468D0524 antikoerper, daam1l antikoerper, fc83b10 antikoerper, si:ch211-87i20.1 antikoerper, wu:fc83b10 antikoerper, dishevelled associated activator of morphogenesis 1 antikoerper, dishevelled associated activator of morphogenesis 1 S homeolog antikoerper, dishevelled associated activator of morphogenesis 1a antikoerper, dishevelled associated activator of morphogenesis 1b antikoerper, DAAM1 antikoerper, Daam1 antikoerper, daam1.S antikoerper, daam1a antikoerper, daam1 antikoerper, daam1b antikoerper

Hintergrund: Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein.

Molekulargewicht: 123 kDa

Gen-ID: 23002

UniProt: Q9Y4D1

Pathways: WNT Signalweg