Coagulation Factor X Antikörper (C-Term)

Produktnummer ABIN5530935

Produktdetails anti-Coagulation Factor X Antikörper

Target: Coagulation Factor X (F10)

Bindungsspezifität: AA 351-381, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coagulation Factor X Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This F10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-381 amino acids from the C-terminal region of human F10.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Coagulation Factor X

Target: Coagulation Factor X (F10)

Andere Bezeichnung: F10 (F10 Produkte)

Synonyme: FX antikoerper, FXA antikoerper, Cf10 antikoerper, fX antikoerper, fi12c10 antikoerper, wu:fi12c10 antikoerper, F10 antikoerper, f10 antikoerper, coagulation factor X antikoerper, Coagulation factor X antikoerper, coagulation factor 10 L homeolog antikoerper, F10 antikoerper, f10 antikoerper, CpipJ_CPIJ012712 antikoerper, CpipJ_CPIJ014863 antikoerper, CpipJ_CPIJ016937 antikoerper, CpipJ_CPIJ017791 antikoerper, fa10 antikoerper, f10.L antikoerper

Hintergrund: F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.

Molekulargewicht: 55 kDa

Gen-ID: 2159

UniProt: P00742