Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogen
This Bmp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-986 amino acids from the C-terminal region of human Bmp1.
BMP1
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
2 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
OI13 antikoerper, PCOLC antikoerper, PCP antikoerper, PCP2 antikoerper, TLD antikoerper, Pcp antikoerper, Tld antikoerper, BMP1 antikoerper, submp antikoerper, tld antikoerper, xtld antikoerper, bmp-1 antikoerper, pcolc antikoerper, xbmp1 antikoerper, tolloid antikoerper, BMP-1 antikoerper, bmp1 antikoerper, bmp1a antikoerper, bone morphogenetic protein 1 antikoerper, Bone morphogenetic protein 1 antikoerper, bone morphogenetic protein 1 S homeolog antikoerper, bone morphogenetic protein 1, like antikoerper, BMP1 antikoerper, Bmp1 antikoerper, bmp1 antikoerper, bmp1.S antikoerper, bmp1l antikoerper
Hintergrund
The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.