CXCR6 Antikörper (C-Term)

Produktnummer ABIN5518702

Produktdetails anti-CXCR6 Antikörper

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Bindungsspezifität: AA 331-351, C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 6(CXCR6) detection. Tested with WB, IHC-P in Mouse,Rat.

Sequenz: EDSSKTCSAS HNVETTSMFQ L

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 6(CXCR6) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: chemokine(C-X-C motif) receptor 6
Protein Name: C-X-C chemokine receptor type 6

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bonzo(331-351aa EDSSKTCSASHNVETTSMFQL), different from the related rat sequence by two amino acids, and from the related human sequence by three amino acids

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu CXCR6

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Andere Bezeichnung: CXCR6 (CXCR6 Produkte)

Synonyme: BONZO antikoerper, CD186 antikoerper, STRL33 antikoerper, TYMSTR antikoerper, BB217514 antikoerper, C-X-C motif chemokine receptor 6 antikoerper, chemokine (C-X-C motif) receptor 6 L homeolog antikoerper, chemokine (C-X-C motif) receptor 6 antikoerper, CXCR6 antikoerper, cxcr6.L antikoerper, Cxcr6 antikoerper

Hintergrund: CXCR6(Chemokine,CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al.(1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al.(2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al.(2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation.

Synonyms: C X C chemokine receptor type 6 antibody|C-X-C chemokine receptor type 6 antibody|CD 186 antibody|CD186 antibody|CD186 antigen antibody|CDw186 antibody|Chemokine(C X C motif) receptor 6 antibody|Chemokine C X C motif receptor 6 antibody|Chemokine C-X-C Motif Receptor 6 antibody|Chemokine CXC motif receptor 6 antibody|Chemokine receptor 6 antibody|CXC chemokine receptor type 6 antibody|CXC R6 antibody|CXC-R6 antibody|CXCR 6 antibody|CXCR-6 antibody|CXCR6 antibody|CXCR6_HUMAN antibody|G protein coupled receptor antibody|G protein coupled receptor bonzo antibody|G protein coupled receptor STRL 33 antibody|G protein coupled receptor STRL33 antibody|G protein coupled receptor TYMSTR antibody|G-protein coupled receptor bonzo antibody|G-protein coupled receptor STRL33 antibody|STRL 33 antibody|STRL33 antibody|TYMSTR antibody